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27 Specifically, vitamin E (α-tocopherol, an isoform of vitamin E) efficiently detoxifies hydroxyl, perhydroxyl and superoxide free radicals, whereas γ-tocopherol (another isoform of vitamin E) appears to be more efficiently implicated in trapping NO radicals.
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The ability of the purified Sap proteases to efficiently degrade Hst-5, further implicated the Saps in the degradation of Hst-5.
A fundamental problem in network biology is the reconstruction of a subnetwork that underlies a process of interest by efficiently connecting a set of implicated proteins (e.g. derived by some genome-wide screen) in a network of physical interactions.
With this strategy, all exons in the genome or selected regions implicated in disease can be efficiently enriched (23– 23).
The protein we used for this experiment was LidL, which is a 489-residue protein from Legionella pneumophila that has been implicated in the ability to efficiently manipulate host cell trafficking events once internalized into host cells.
Despite common variations in the innervation and branching of the femoral, medial, and lateral femoral cutaneous nerves and saphenous nerves, anatomical treatment lines were defined using the results of this study to efficiently and effectively locate and target the sensory nerves implicated in superior and inferior knee pain.
However, TPR repeat regions have been implicated in the ability of L. pneumophila to efficiently establish infection and/or to manipulate host cell trafficking event [37].
When HIV-1 virus-like-particles (VLPs) are produced in the presence of TRIM5αrh, TRIM5αrh is efficiently incorporated into VLPs, implicating the interaction between cellular and viral components during viral assembly [16].
Here, we demonstrate that scL crosses the BBB and efficiently targets GBM, as well as cancer stem cells (CSCs), which have been implicated in recurrence and treatment resistance in many human cancers.
That Beijing strains have been implicated in many outbreaks of TB suggests that they may be more efficiently transmitted or have an enhanced ability to progress to active disease than do other strains.
Therefore, we next verified whether CAD endonuclease was implicated in SAHA effects by using two shRNAs against CAD mRNA that efficiently downregulate CAD protein levels in U251-MG cells.
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