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The interface traps are efficiently cured by N2 annealing.
With genome editing tools, stem cell lines from patients can be efficiently "cured" to correct the disease relevant genetic variants to establish isogenic control groups (Fig. 1A).
With genome editing tools, stem cell lines from patients can be efficiently "cured" to correct the disease relevant genetic variants; or wild-type stem cells can also be introduced with genetic variants to create "patient" cell lines for disease modeling (A).
Many diseases, including cancer, could be efficiently cured if early diagnosed.
We found that the BAG domain alone of Snl1 efficiently cured [URE3], but the entire cytosolic domain failed to do so.
At 30°C, [ PSI + ] propagation is stable in both of these strains; however at 40°C, both were now efficiently cured (e.g. ∼100% for WT/ G58D, ∼60% for SUP35/Δ).
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Image-guided therapy is one of the most promising strategies for efficiently curing a tumor.
Characterization of phenotypes associated with virulence plasmids requires a system for efficiently curing strains of their virulence plasmids.
In addition, PRP treatment in combination with the cell therapy could more efficiently cure patients with the patellar tendinopathy.
Given the variation in the effects of mutants upon [ PSI+] propagation and also heat shock we were surprised to discover that all the Sse1 mutants were unable to efficiently cure the [ URE3] prion.
Cationic photopolymerizations of multifunctional epoxides cure efficiently at room temperature.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com