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The bispecific DARPin construct was the most potent one, efficiently blocking the IgE FcɛRI interaction and preventing the release of proinflammatory mediators.
Besides the above optical and electronic metrics, the band alignment in the multi-component system favors the directed flow of photogenerated electrons from BiOX and TiO2 to Ag, thus efficiently blocking the recombination of the e− h+ pairs.
Both types induce immunity to polio, efficiently blocking person-to-person transmission of wild poliovirus, thereby protecting both individual vaccine recipients and the wider community (so-called herd immunity).
In the present study, we demonstrate that STAT3 decoy ODN can suppress lung cancer cells in vitro and in vivo by efficiently blocking STAT3 signaling, suggesting the therapeutic potential of STAT3 decoy ODN in treatment of human lung carcinoma.
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We show that AAVR directly binds to AAV2 particles, and that anti-AAVR antibodies efficiently block AAV2 infection.
NF54_SpzPfEMP1-specific antibodies efficiently block hepatocyte infection in a strain-specific manner.
Also, both overexpressing a dominant-negative TROY or presence of a soluble TROY protein can efficiently block neuronal response to myelin inhibitors.
Co-expression of dCas9 and sgRNA can efficiently block transcription (in bacteria, ~ 300-fold repression) by interfering with transcriptional elongation, RNA polymerase binding, or transcription factor binding.
Before tumors form, these events result in early dissemination microenvironments that propel active intravasation and dissemination to the lung, which was efficiently blocked by macrophage depletion.
In this condition, B49Mod1 efficiently blocked adhesion of incoming-treated cancer cells to untreated cancer cell monolayer in a BST-2-dependent manner (Fig. 3F).
Vaccines to efficiently block or limit sexual transmission of both HIV and human papilloma virus (HPV) are urgently needed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com