Exact(6)
It is expected that similar T4SS regulators will be identified in other Rickettsiales genomes, given the need to tightly regulate all of the scaffold components for efficient transporter function.
Conversely, hCNT3 appears to be an efficient transporter of AZT, ddC and ddI (Minuesa et al., 2008).
This Dk value is elevated in hydrogel lenses due to the greater volume of water present, water being an efficient transporter of oxygen.
Therefore, the present study demonstrates that Hxt11 is a more efficient transporter for ethanol production on sugar mixtures containing glucose and xylose as compared to the heterologously expressed specific xylose transporters mentioned above.
It would be interesting to reconstitute plant transporters in engineered yeast to see if plants have evolved an efficient transporter for a specific class of natural product such as sesquiterpenoids.
Maliepaard et al showed that BCRP, which also belongs to the ATP-binding cassette transporter family, appears to be a highly efficient transporter of topoisomerase I inhibitors in cell lines without overexpression of the multidrug resistance-associated pumps MDR1 and MRP1 (Maliepaard et al, 1999).
Similar(54)
Owing to the native transport characteristics of yeast, efficient transporters may need to be discovered through the use HXT family knockout strains [ 77].
The AAAPs are efficient transporters of osmoprotectants such as proline, glycinebetaine and gamma-aminobutyric acid [ 52] that accumulate in higher plants under stress conditions.
A high level of araA expression is notably important in establishing an efficient L-arabinose pathway in S. cerevisiae, and more efficient transporters are necessary to improve the L-arabinose absorption capacity of the evolved strains.
The AAAPs are efficient transporters of proline and betaine [ 52] that accumulate in higher plants under stress conditions such as drought, salinity, extreme temperatures, UV radiation, and heavy metals [ 53, 54].
This may provide a partial explanation to the previous observation that the ABC exporter, transporter associated with antigen processing (TAP), becomes a bidirectional, yet low-efficient transporter when mutations occur in its NBD dimer (Grossmann et al., 2014).
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