Sentence examples for efficient to activate from inspiring English sources

For example, it is not efficient to activate the sensors all the time for only the benefit of a fast response.

For this reason, although mTORC1 is inhibited, mTORC2 may still remain efficient to activate S473-AKT and maintain cancer cell survival.

We found that treatment of MM cell lines with Hsp90 inhibitors [radicicol or 17-allylaminogeldanamycin (17AAG)] results in a significant upregulation of MICA and MICB expression, rendering these cells more efficient to activate NK cell degranulation [ 22].

However, the incubation of stressed, apoptotic tumor cells with syngeneic DCs is generally not strong enough to generate protective immunity, suggesting that the uptake of apoptotic cells by DCs alone may not be sufficiently efficient to activate an immune response, as described by others [ 37].

Our results indicate that increased levels of nitric oxide can upregulate PVR/CD155 cell surface and mRNA expression in MM cells; in addition, exposure to nitric oxide donors renders myeloma cells more efficient to activate NK cell degranulation and enhances their ability to trigger NK cell-mediated cytotoxicity.

Heat activation for 20 min at 55°C is an efficient method to activate purified proteasomes [30], [31].

She had noticed that when NPR hit "rough patches" — say, the firing of the news analyst Juan Williams and failed attempts by Republicans to bar federal funding to the organization — "there was no efficient way to activate our most loyal fans".

Because HCV does not efficiently infect human cells in vitro and primary infected hepatocytes cannot be used as stimulator/target cells for CTL analysis, development of efficient systems to activate and expand CTL in vitro, reproducing antigen presentation to CTL occurring during natural infection, is mandatory to study CTL activity and to define the hierarchy of immunodominance of CTL epitopes.

Ubiquitination of TBK1 seemed an efficient tactic to activate IFN response because the endogenous TBK1 was K63-linked poly-ubiquitinated at 8 h post Sendai virus (SeV) infection (Fig. 1A, top panel) and accompanied with phosphorylation of IRF3 and STAT1, the indications of the IFN production (Fig. 1A, panels 4 5).

Virus-induced gene silencing (VIGS) is one of the most efficient approaches to activate the PTGS process.

This observation has inhibited, by now, the routine use of IP in human liver surgery and has indicated the need of more efficient approaches to activate IP in patients.