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Hockemeyer, D. et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Grizot, S. et al. Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease.
Cells transfected with Cas9 tracrRNA crRNA resulted in populations where over 60% of the AAVS1 loci contained InDels, indicating efficient targeting of Cas9 nuclease activity to this site.
We demonstrate a clinically feasible strategy for efficient targeting of the KRT14 gene in normal and EB-affected human keratinocytes.
The first approach, efficient targeting, focuses on areas with high forest carbon content, high deforestation risk and low opportunity cost.
Efficient targeting occurred only with an exposed ligand and a dense concentration of peptide (6000 peptides/particles).
Bonifaz, L. et al. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance.
Presented approach can be applied in the risk management, to support an efficient targeting of the risk reduction measures, or to improve a design of the national monitoring.
Knowledge of the significance of hotspot zones would enable more accurate calculation of total farm emissions and more efficient targeting of N2O mitigation strategies.
That allows for more efficient targeting.
To enable efficient targeting longer-lived α-particle emitters are required.
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