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RNase H enables efficient repair of R-loop induced DNA damage.
Vahidi Ferdousi, L. et al. More efficient repair of DNA double-strand breaks in skeletal muscle stem cells compared to their committed progeny.
Cellular aging is linked to deficiencies in efficient repair of DNA double strand breaks and authentic genome maintenance at the chromatin level.
This new modification method of porous PLGA microspheres proposes a route toward efficient repair of tissue defects at reduced risk and cost level.
In the study, highly efficient repair of the mutant allele was achieved using the wild-type (WT) allele in heterozygous human zygotes through CRISPR/Cas9 (Ma et al., 2017).
However, the efficient repair of tumors frequently prevents successful treatment.
However, the efficient repair of DNA DSBs in the tumors makes the tumors radioresistant, which frequently prevents successful treatment.
It is possible that Swi1 Swi3 facilitates efficient repair of broken replication forks, although further investigation is needed to address this possibility.
Overall, these results suggest that compared to PBS, rhGas6 treatment resulted in more efficient repair of the corpus callosum following cuprizone toxicity.
Resistance mechanisms discussed include the expression of multidrug resistance transporters, slow cycling, efficient repair of DNA damage and a high expression of antiapoptotic proteins [6], [7].
Therefore, we also speculate that improper cohesion in the absence of Swi3 can affect efficient repair of DSBs at replication forks when cells are treated with camptothecin.
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