Sentence examples for efficient initiation from inspiring English sources

When the 1793 human AltORFs were filtered for the presence of an optimal Kozak context around the initiator AUG codon, known to be extremely important for efficient initiation of translation (19), this number dropped to 217 putative AltORFs.

Packed with glass beads, the hot-zone reactor resulted in more efficient initiation and film growth.

Extracellular stimuli imposed on stem cells enable efficient initiation of mechanotransductive signaling to regulate stem cell fates; however, how such physical cues conferred by the stereo-topographical matrix govern the fate of stem cells still remains unknown.

Deletion of cofB produces a phenotype with no detectable pili formation on the cell surface, while molecular modeling indicates that the characteristic homo-trimeric structure of CofB is well situated at the pilus tip of colonization factor antigen/III formed by the major pilin CofA, suggesting a role for the minor pilin in the efficient initiation of T4P assembly.

The root stocks 3309C, 110R, 41B, Rupestris St. Georges, Fercal, SO4 and the Vitis vinifera genotypes Chardonnay, Chasselas blanc, Cabernet Sauvignon, Gewurztraminer, Grenache, Merlot, Muscat Ottonel, Pinot Meunier, Pinot Gris, Pinot Noir, Sauvignon, Syrah and five different clonal accessions of Riesling were amenable to reproducible efficient initiation of regenerable embryogenic callus.

The assigned start codon of human RNase ZL (ELAC2) appears to be in a suboptimal configuration for efficient initiation of translation (Figure 2).

This codon organization would ensure efficient translation initiation, release, and recycling of the initiator tRNA for the next round of initiation.

Within the Kozak motif, the most important nucleotides for efficient translation initiation are the R in position -3 and the G in postion +4 relative to the initiation codon [ 25, 26].

Also other, less important determinants for efficient translation initiation (C−4 and C−2) conform more closely to the consensus sequence in the case of the second putative initiation site.

In particular, our results indicate that increased stability of 5′ mRNA secondary structures in the E. coli optimized transcript prevents efficient translation initiation in the absence of the phoA leader sequence.

This chapter presents the construction and evaluation of a series of expression-secretion vectors with strong constitutive or regulatable promoters and efficient translation initiation regions designed for intra- and extracellular expression of homologous and heterologous proteins.