Sentence examples for efficient esc from inspiring English sources

Combining two inhibitors (2i) of the Erk pathway and of glycogen synthase kinase-3 with LIF (2iL) provides a defined culture system that is effective for all strains of mouse and rat tested, supporting efficient ESC derivation and clonal expansion from dissociated cells (Boroviak et al., 2014; Ying et al., 2008).

Indeed, it has recently been shown that Otx2 is required for efficient differentiation of ESCs in vitro and conversely that loss of Otx2 destabilizes the differentiated state.

Using even unoptimized 5′-Anch100-C24/3′-cA20-C16, we found efficient adhesion between ESCs and complementary 7 μm diameter spots of DNA patterned on glass surfaces, allowing the preparation of live, single cell microarrays with more than 95% occupancy.

Our findings proposed that hypoxic priming of ESCs might be an efficient means of inducing ESCs into specialized lineage such as vascular-commitment.

The haplosufficient Terc+/- ESCs had significantly reduced ESC mice production efficiency compared with wild type ESCs.

Gene expression and differentiation profiles in human NT-ESCs were similar to embryo-derived ESCs, suggesting efficient reprogramming of somatic cells to a pluripotent state.

We previously established an efficient system to induce ESC neural differentiation in serum-free medium (Zhang et al., 2010a).

The external peptide pulsing of targets was apparently so efficient that even maGSCs, ESCs, iPSC and F9 cells, on which no H2Kb molecules could be detected by flow cytometry, were readily killed in a peptide-specific manner.

8 This protocol has multiple advantages: 1) the techniques were relatively simple, and ESCs were only seeded onto the PA6 stromal cells feeder to form colonies; 2) neural differentiation of ESCs is efficient and speedy; and 3) no exogenous reagent was used.

The application of ESCs in bone regenerative medicine requires the development of efficient of methodologies for differentiating ESCs into the osteoblast lineage in vitro and functional bone formation in vivo.

These studies suggest that DNMT inhibition is an efficient inducer of EC differentiation from ESC.