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The objective of this study was to evaluate the effects of the extraction parameters (ethanol graduation, previous shaking time in an ultrasound bath and drug/solvent ratio) on the yield of artemisinin in the liquid extract obtained by percolation from A. annua and then optimize the extraction efficiency of this compound.
Although we obtained functional effect with one-eightieth of the normal AON dose regimen, the efficiency of this compound was relatively unsatisfactory in terms of size, AON loading capacity, and efficiency of treatment.
This means that, besides answering the question of whether an inhibitor candidate could efficiently block the MEP pathway, the exploitation of the same set of data would allow a direct comparison of the efficiency of this compound with established MEP pathway inhibitors.
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For example, the enhancement efficiency of the compound 2 for Zn2+ is up to 846%.
We then defined the efficiency of the compound in a malaria mouse model and found that the compound inhibited parasite growth and cleared parasitemia in treated mice at extremely low doses (130 µg/kg).
Electrochemical measurements showed that the inhibition efficiency of these compounds increased with increase in their concentration.
The highest power conversion efficiency of these compounds is 2.01% after thermal annealing.
The efficiency of these compounds as antimicrobial agents was increased with the hydrophobicity and spacer length of the gemini ionic liquids.
The removal efficiency of these compounds by EB processing is discussed regarding diverse conditions, such as differences in initial concentrations, background gases, absorbed doses, and relative humidity.
The inhibition efficiency of the compounds are calculated and tabulated in Table 1.
The extraction efficiency of the compounds was determined by spiking blank serum samples prepared in human serum albumin.
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