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Computer-aided approaches are widely used in modern medicinal chemistry to improve the efficiency of the discovery phase.
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Here, we show that manufacturing is not only a central component of product success, but also that, by integrating manufacturing and discovery activities in a "holistic" interpretation of QbD methodologies, we could expect to increase the efficiency of the drug discovery process as a whole.
The WHO argues that transparency could even improve the efficiency of the drug discovery process.
They found the similar: algorithm trading increased the efficiency of the price discovery process.
Unenlightened fund managers form erroneous estimates of GETF units' prices distorting thus the efficiency of the price discovery mechanism.
Thus, the efficiency of the drug discovery process potentially could be further improved through better use of structural information.
This framework aims at reducing the search range and cost as well as enhancing the efficiency of the resource discovery process.
We also discuss the design of the API and describe experimental results characterizing the fairness of the bus algorithm, the efficiency of the peer discovery algorithm, and the performance of the SSN system under varying load conditions.
However, for many crop species the efficiency of the SNP discovery process is often hampered by the fact that limited amounts of genome sequences are available compared to e.g. Arabidopsis and rice, for which draft genome sequences have been completed [1], [2].
Inclusion of wild isolates from other locations worldwide may increase the efficiency of the SNP discovery approach.
This study aimed to address, among others, the following goals: to (i) provide a standard mitochondrial preparation and analysis protocol with Ion PGM™ (Life Technologies), (ii) evaluate the efficiency of the variant discovery tools, and (iii) estimate the best software to obtain high-quality results.
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