Sentence examples for efficiency of hybridization from inspiring English sources

However, from the beginning, antisense strategies have faced several obstacles, such as in vivo stability of the oligonucleotide, cellular uptake, efficiency of hybridization of the antisense agent to the mRNA target, selectivity of oligonucleotide binding, and inhibition of gene expression.

Folding of the probes affects the efficiency of hybridization (Binder et al., 2004).

Several approaches to improve the efficiency of hybridization have been described.

We are now assessing the efficiency of hybridization by conducting artificial cross-hybridization microarray experiments (in preparation).

Next, let κ i > 0 be the overall efficiency of hybridization, scanning, image analysis, etc., for array i relative to the first array, such that κ1 = 1.

The Affymetrix eukaryotic hybridization control kit and Poly-A RNA control kit were used to ensure efficiency of hybridization and cDNA amplification.

However, it had not been extensively explored whether the sequence divergence could affect the efficiency of hybridization-based capture systems designed based on a reference genome (C57BL/6 J) when applied in the study of distantly-related strains.

To verify the efficiency of the hybridization step we examined the results of the hybridization spike-in controls provided for the Affymetrix GeneChip (QC1).

In our experiments, the increased trend of bioB, bioC, bioD, and cre in their signal values was observed (Table 2), which suggest that the hybridization, washing, and staining were successful and the efficiency of sample hybridization reached expectation.

Critical factors affecting detection efficiency of targets hybridization on microarray are the design of capture probes, the way they are attached to the support, and the sensitivity of the detection method.

It is well known that an efficiency of DNA hybridization directly depends on the ionic strength of medium.