Sentence examples for efficiency element from inspiring English sources
The cis-acting elements are located in the AAV inverted terminal repeats (ITRs), which can fold into a palindromic T-shaped hairpin, and in the AAV p5 promoter, which contains a sequence dubbed the p5 integration efficiency element (p5IEE) [7].
This motif corresponds to the efficiency element, originally identified ∼50 nt upstream of mRNA cleavage sites.
Hrp1 specifically binds the UAUAUA efficiency element via its tandem RRM domains (Pérez-Cañadillas, 2006).
This indicates that Hrp1 binds directly to the efficiency element to promote 3′ processing of mRNAs and SUTs, but binds in a more distributed manner throughout CUTs.
For mRNAs and SUTs we detected the hallmarks of cleavage and polyadenylation, including an appropriate configuration of sequence elements, a Pab1-bound poly(A) tail, and Hrp1 bound to an efficiency element ∼50 nt upstream of the pA site.
In this regard, because no sequence motif equivalent to the yeast AU-rich efficiency element or the mammalian UGUAN sequence was observed among the putative 3′-end-processing signals in A. oryzae, the RNA-binding specificity and positioning of the homologs Hrp1 and CFIm25 involved in 3′-end-processing in A. oryzae must be investigated.
Two efficiency elements located upstream of the PAS have been reported to promote polyadenylation.
The best sequence for yeast efficiency elements is UAUAUA and its single nucleotide variants (UAUGUA and UACAUA).
In addition to A-rich sequence elements, further upstream elements, designated efficiency elements in yeast or far upstream elements in plants, the cleavage site, and the downstream U-rich element flanking the cleavage site have been described.
> -wrap-foot> > -wrap-foot> Predominant sequence motifs in the upstream of the A-rich region (region I), called efficiency elements in yeast and far upstream elements in plants, have been identified.
This element resides in a similar position to efficiency elements that modulate 3' end formation in mammals and yeast [ 25], and bears a base composition reminiscent of downstream sequences involved in 3' end formation in mammals.
