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Exact(26)
Efficacy was based on the number of migraine headache days reported in the subjects' headache diaries over sequential 4-week periods for the duration of the trial.
For predialysis patients, efficacy was based on pooled patient level data of predialysis and dialyzed patients due to low number of predialysis patients treated with LC.
Lack of efficacy was based on a failure to induce antibodies capable to bind epitopes in the context of functional OPN protein.
Demonstration of efficacy was based on reduction in migraine frequency and use of acute medication, improvement of quality of life evaluated by the Migraine Specific Questionnaire (MSQ) and the Short-Form36 (SF36).
For PCV13, assumption on IPD efficacy was based on clinical data for PCV7 in children for all patients, expecting similar levels of efficacy against the additional 6 serotypes which are not included in PCV7.
Efficacy was based on a reduction in organism burden in treated vs untreated mice determined by microscopic quantification.
Similar(34)
Among the problems with using fMRI for lie detection, for instance, is the fact that the studies demonstrating its efficacy are based on lies about trivial matters — say, what playing card you've been shown — elicited in laboratory situations, in which mostly healthy, young, non-criminal subjects are instructed to lie.
Early stopping rules for efficacy are based on the observed difference in PaO2/FiO2 ratio.
The proof of its efficacy is based on four randomized, placebo-controlled trials of 853 patients, showing an improvement in functional outcome [32 36].
The current evidence of efficacy is based on relatively small sample sizes per study – with the exception of Ruiter et al. (2015) – and only one to three training sessions per condition.
However, there is a risk that trial durations will be unfeasibly long if methods for evaluating safety and efficacy are based on the best overall response and toxicity during trial design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com