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All trough concentration patients were superior to the efficacy target (2 mg/L).
An achievable efficacy target needs to be set while standardisation of trial outcomes and critical choices based on the vaccine development pipeline need to be made.
Primary outcomes Efficacy (target vessel revascularisation) and safety (death, myocardial infarction, stent thrombosis).
No efficacy target was predefined since antitumor activity was a secondary objective of the trial.
The context score threshold for high efficacy target was set at −0.2.
Outcomes Long term efficacy (target vessel revascularization, target lesion revascularization) and safety (death, myocardial infarction, stent thrombosis).
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Also, multi-functionalized nanostructures are characterized by enhanced bioavailability, efficacy, targeted localization, active cellular uptake, and low side effects.
The introduction of novel technologies has the potential to support the development of vaccines with increased efficacy targeting infections as well as non-communicable diseases.
This outcome depends more on manufacturers' ability to produce LEDs that follow DOE's lamp production cost and efficacy targets, than on reducing power electronics costs for DC building circuits and voltage standardization.
The recombinant adenovirus presented in this work showed potent antitumor efficacy targeting AFP-positive HCC.
Due to their fantastic efficacy, targeted cancer therapies have been accepted as a great success in treating many types of cancer [2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com