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This enabled to show that increasing values of drug efficacy result in an initial faster decline of viral load followed by a slower second phase.
Also predefined sensitivity analyses confirmed our primary efficacy result.
The previous confirmative study in Japan did not have a successful efficacy result [ 25].
By contrast, analyses often use the "last observation carried forward" (LOCF) approach, which can lead to an inflated efficacy result.
The efficacy result showed that CDTHD from 21.6 g/kg⋅d to 86.4 g/kg⋅d exhibited significant hepatoprotective effect against ANIT-induced acute cholestatic hepatitis.
Another important aim of the study was to investigate the efficacy result of individual gene or drug treatment and compare it with therapeutic outcome of gene/drug combination treatment.
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Up to this point, Gilman had been given access to the safety results of the trials, but he had been "blinded" to the all-important efficacy results.
Secondary efficacy measures confirmed primary efficacy results.
Efficacy results need to be interpreted with caution.
Efficacy results from clinical trials are expected in 2015.
Advances in this field are required to substantiate the efficacy results.
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