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Given the difficulties in measuring the infectivity of primary HCV strains, clinical studies measuring IFN efficacy rely on genomic RNA measurements and may underscore the impact of early IFN doses.
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Interestingly, the study of tumor cell death biology has recently revealed that part of radiotherapy efficacy relies on its ability to trigger an immune response against tumor cells.
Medicinal herbs are by nature complex, and their efficacy relies on multi-target intervention via their multiple active components.
Parameter estimates, such as the ingestion rate and treatment efficacy, relied on data from the literature, each with its own set of assumptions.
Our findings are therefore concordant with a model in which SDNVP efficacy relies on the inhibition of the majority of circulating strains.
Taken together, these observations raise the possibility that it might be technically challenging to develop live sporozoite immunization protocols whose efficacy relies on arrested hepatic stage development.
Treatment efficacy relies on a compromise between the quality of tumor control achieved by radiation therapy and the damages generated on intestinal healthy tissues; this is referred to as the benefit/risk ratio [ 1].
In most of the cases, evaluation of therapeutic efficacy relies on the quantification of different lesions (neuronal loss/abnormal PrP accumulation) in tissues, which requires killing of the subjects.
At this end, acarbose should also exploit the assumed beneficial CV effects of DPP-4 inhibitors, whose efficacy rely heavily on the functional capacity of the residual beta cell mass to modulate insulin secretion in response to available, slowly dissipating endogenous GLP-1 [ 38, 39].
We encourage broad and creative engagement with and application of this tool, whose long-term accuracy and efficacy will rely on updates, edits, and improvements arising from user interactions.
Its efficacy relies only on the local low dimensionality of the underlying model dynamics, not on the equations themselves, and so provides a flexible state update scheme even as the models themselves are improved.
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CEO of Professional Science Editing for Scientists @ prosciediting.com