Rationale Lengthy multi-drug, toxic, and low efficacy regimens limit management of pulmonary nontuberculous mycobacterial (PNTM) disease.
Besides limited efficacy, this regimen is associated with substantial gastrointestinal toxicities, including nausea, mucositis and oesophagitis (Herskovic et al, 1992; Al-Sarraf et al, 1997).
In the absence of evidence of the efficacy of regimen D started after 28 weeks but before 36 weeks of gestation, we assume the same efficacy if treatment is started before 34 weeks, and the lower efficacy of regimen A for those starting after 34 weeks.
However, it is hard to compare directly the efficacy of regimens because the classifications of chemotherapy regimens in both studies were different.
We predict the efficacy of regimens containing different doses and frequencies of isoniazid and rifampin.
We particularly analyzed the efficacy of regimens: G vs. F and with P vs. without P.
We analyzed the efficacy of regimens: gemcitabine (G) versus fluoropyrimidine (F) and with or without platinum (P).
These kinds of support with diabetes management appear to be associated with increased patient self-efficacy, medication regimen adherence, and better health outcomes [ 41, 42].
The comparable efficacy of regimens substituting capecitabine for infused 5-flurouracil has been directly studied in two phase III trials: the REAL-2 study and the ML17032 study.
The treatment effect did not differ significantly between the laxatives, treatment regimens or expected efficacy of the regimens.
