This in general could not be confirmed in the protocols using diclazuril, which showed a much lower and mostly variable efficacy pattern.
The data presented indicate an advantageous safety profile and efficacy pattern of PXL150, which warrants further clinical investigations of the potential of this peptide in the treatment of SSTIs.
Although the exact contribution of the active metabolite SU12662 to the toxicity and efficacy pattern of sunitinib in humans is unknown, preclinical data point towards equipotent inhibitory capacities (Baratte et al, 2004).
25 Since there is an order of magnitude difference between efficacy pattern by different inhibitors, where uncompetitive inhibitors seem to be the most potent, it might be relevant to interrogate what value GKD brings to the anti-infective drug-discovery programs.
These differences may account for some of the observed variations in potency, disease-specific efficacy, safety patterns, and speed of onset and offset of action (Russell 2007).
To assess the feasibility, efficacy and patterns of gene transfer methods, there is a real need for simple and precise methods of evaluation.
58 The study will be a 5-year prospective multicentered noninterventional study to assess the long-term safety, efficacy, treatment patterns, and health-related quality of life outcomes in patients being treated with ranibizumab.
25 Additionally, the LUMINOUS programme was initiated as part of an ongoing pharmacovigilance programme for ranibizumab, it was designed to assess long-term safety, efficacy, treatment patterns, and health-related quality-of-life outcomes in a large number of patients treated with ranibizumab in routine clinical practice across the world.
Our objective was to analyze treatment efficacy, current practice patterns and utilization of anesthesia.
