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There were no statistically significant differences in any key secondary efficacy outcome between vortioxetine and placebo.
As a primary efficacy outcome for clinical trials it can be quantified over a continuous scale.
Response rates to lithium compared with placebo or other active drugs will be the primary efficacy outcome.
In all six studies, efficacy assessments included the YMRS total score (primary efficacy outcome) and the MADRS Total score.
RCTs evaluating pain treatments typically use average pain intensity (API) or worst pain intensity (WPI) as the primary efficacy outcome.
The primary efficacy outcome in trials of urate lowering therapy (ULT) for gout is serum urate (SU).
The efficacy outcome was based on recurrent VTE and death due to VTE during the 3-month treatment period.
For all other pre-specified efficacy outcome measurements, no difference was found between the efficacy of telcagepant and rizatriptan at 2 h [19].
Primary efficacy outcome was change from baseline in 30-Item Inventory of Depressive Symptomatology Clinician-Rated (IDSymptomatology Clinician-RatedSafety and tolerability were monitored.
aPrimary efficacy outcome.
bPrimary efficacy outcome.
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