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Thus far, combination therapy with aliskiren and ACE inhibitors or angiotensin receptor blockers has shown efficacy only on surrogate end points.
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In James Herbert's world, things go bump in the night with spine-tingling efficacy only to carry on bumping, thumping and violently swaying until the tension is interspersed by laughter.
Some studies have found that the administration of carbapenems by continuous infusion maintain constantly concentrations above the MIC of susceptible organisms over the course of therapy; but limited data exist on clinical efficacy (only occasional observations have been made).
Threat and efficacy interact in their effects on behaviour, such that threat only has an effect if efficacy is high, and efficacy only has an effect is threat is high.
Its efficacy relies only on the local low dimensionality of the underlying model dynamics, not on the equations themselves, and so provides a flexible state update scheme even as the models themselves are improved.
This makes sense: biologics are notoriously tricky to manufacture, and both their safety and efficacy depends not only on the specific protein sequence of the molecule, but on the highly specific culture conditions used to manufacture it.
It seems unrealistic to imagine that sex only functions on the efficacy with which selection operates on only one or other of these types of mutation.
In addition to this convincing efficacy, patients required on average only one transfusion every 6 to 7 weeks, which is convenient and may help to maintain treatment compliance.
This study explored patients' satisfaction with the efficacy of CAM based only on subjective perceptions and cannot provide evidence-based data on efficacy.
But for vancomycin, in contrast to the beta-lactams, we expected this; as we have seen, AUC24h/MIC is the PK/PD parameter best predictive of clinical efficacy and is dependent only on TDD and renal function.
Its functionality and efficacy are dependent not only on the thickness of the MGL but also on its chemical composition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com