We propose that susceptibility to chytridiomycosis in this case is not necessarily due to lack of acquired immune responses, but instead is caused by some failure in the efficacy of the responses.
A comparison at day 0, on the other hand, stands to better highlight genes responsible for differences in the efficacy of the initial response to the bacteria, assuming that some of these genes exhibit expression differences prior to infection.
The more serious concern is the efficacy of the proposed response.
"[The plaintiffs'] evidence raises serious questions as to the efficacy of the emergency response," he wrote.
The efficacy of the chemotactic response is comparable to the stimulation with the chemokine CCL2 which binds to the endogenous CCR2.
As cytokines function as signal molecules in infection, the defensive efficacy of the immune response is mediated by immune cells, antibacterial peptides and the complement system.
To test the efficacy of the antibody response elicited by PA-Av-C3d3/IFA immunization, we compared the ability of the various immunogens to provide protection against intranasal Sterne strain B. anthracis spore challenge.
While the efficacy of the CTL response does not appear to rely solely on its breadth, it is widely believed that CTL escape has a major impact on disease outcome.
The number of oocysts ten days after infection was used as a measure of the success of malaria infection and the percentage of a bead covered by melanin 24 hours after inoculation was used as a measure of the efficacy of the melanisation response.
