Sentence examples for efficacy of the agent from inspiring English sources

They are primarily safety studies and are, thus, empowered to assess the safety and not the efficacy of the agent.

These results corroborate the view that antitumour activity of 5F 203 is highly dependent on functional AhR signalling, whose impairment results in reduced efficacy of the agent.

Among the variety of factors that can govern such resistance, the short half-life of exogenous sTRAIL can limit the exposure and consequently the efficacy of the agent.

Administration of anti-TNF alone in RA patients can elicit autoantibodies resulting in an enhanced clearance and loss of efficacy of the agent [ 60].

These processes may impinge on the pharmacological efficacy of the agent in vivo and they support further clinical evaluation of 667 COUMATE as a novel chemotherapeutic agent.

Some caregivers who decline enrollment cite doubts about the potential efficacy of the agent under investigation as reason for refusing participation [ 28].

We determined the relative efficacy of the agents by measuring LD50.

Overall, our findings indicate that modifications in all three functional domains of VE analogues (cf Figure 1) modulate the proapoptotic efficacy of the agents.

The antimicrobial efficacy of the agents used for preoperative skin preparation is tested in vitro using both agar plates as well as porcine skin.

One of the outstanding questions in biological control is whether local adaptation occurs following the release of biocontrol agents, and if so, does adaptation enhance the efficacy of the agents (Roderick and Navajas 2003; Hufbauer and Roderick 2005).

Large randomized placebo controlled trials are necessary for investigation of the efficacy of these agents in the improvement of survivals both before and after transplantation.