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Although we have not established linearity of exposure with dose for either compound, this modest efficacy is consistent with the anticipated sub-EC90 free inhibitor blood concentration.
The need for a long duration of vaccine efficacy is consistent with our understanding of the natural history of HPV infection: progression to cervical cancer can take more than 10 years [ 41].
The finding that HRG but not HER3 expression is a predictive biomarker for patritumab clinical efficacy is consistent with the relationship between the HER3 receptor and its ligand and the mechanism of action underlying patritumab activity.
Our finding that the C/C genotype, compared with the C/A or A/A genotype, was associated with poorer treatment efficacy is consistent with studies of cisplatin-treated oesophageal or non-small cell lung cancer patients (Bradbury et al, 2009; Kalikaki et al, 2009).
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The perceptions of safety and efficacy were consistent with use or non-use of herbal medicine.
Treatment efficacy was consistent across subgroups, including age, when BEV was combined with CPT-11-based therapy [ 21].
Almotriptan efficacy was consistent between three attacks, with 56.2% of patients pain-free at two hours at least twice.
Many of these quantitative differences in gene expression efficacy are consistent with the potent agonist activity of EE and the weak agonist activity of TAM.
Prophylactic efficacy was consistent despite differences in age, sex, performance status, treatment context (adjuvant or advanced) and disease type (except possibly non-Hodgkin's lymphoma).
Extension studies of all three drugs have further suggested that long-term tolerability and efficacy are consistent with that observed in the clinical trials [ 13- 17].
Beliefs about safety and efficacy were consistent with patterns of use or non-use, although both users and non-users were unsure about the safety and contraindications of Western medicine during pregnancy compared with that of herbal medicine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com