Sentence examples for efficacy is compromised from inspiring English sources

Hence, although reovirus has shown tremendous potential in in vitro studies and in immuno-compromised animals, its efficacy is compromised when implemented in hosts with an intact immune system.

However, the PDT efficacy is compromised by insufficient selectivity and low solubility.

CONCLUSION: SMF therapy significantly improves disability and may reduce pain when active magnets are worn continuously for 4 weeks in patients with CPP, but blinding efficacy is compromised.

However, their efficacy is compromised by resistance mechanisms, and their dosing is often limited by severe toxicity.

There is no evidence that the efficacy is compromised or toxicity more pronounced in elderly or PS 2 patients.

Numerous studies demonstrate the efficacy of anticoagulation in reducing the risk of AF-related embolic events and preventing hospitalizations, but efficacy is compromised by inadequate and suboptimal treatment patterns.

However, such a mechanism is in contrast to treatment efficacy, which is compromised by resistance mutations if started within 6 18 months after SDNVP exposure [ 3, 4, 14].

However, efficacy of Boceprevir is compromised by the emergence of drug resistant variants.

The therapeutic efficacy of tamoxifen is compromised by its agonistic activity in some tissue types.

As a result, the mandate of the FDA to ensure the enforcement of the federal regulation is weakened, and the safety and efficacy of pharmaceuticals is compromised.

As the efficacy of radiotherapy is compromised by tumour hypoxia and this is a major barrier to successful treatment, we evaluated the combination of radiation and VE-821 in a range of hypoxic conditions (Begg et al, 2011).