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This may become significant as the impact of interindividual variations in protein expression and the effect on drug metabolism and drug efficacy is better understood.
Prior work suggests that HBV vaccination efficacy is better in younger recipients [ 24].
Immunization of mice with pVAX-ROP38 induced significantly reduction of brain cysts (76.6%) in the vaccinated mice compared to the controls, and this efficacy is better than other single gene vaccines including TgIF2α (44.1%) [ 25] and TgCDPK3 (50%) [ 24].
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Analogues with piperazine derivatives 8b showed promising activities against CVB3 with a lower IC50value and higher selectivity index, their efficacy was better than that of the commercialized medicine, Ribavirin.
A 20 mg od dose yielded favourable coagulation results, i.e. the safety margin of an INR 3 warfarin therapy was not exceeded, and efficacy was better than an INR 1.5 therapy (see Figures 3 and 10).
Although the efficacy was better with the every-21-day schedule, treatment with weekly docetaxel is an option for elderly men diagnosed with hormone refractory prostate cancer.
The maximum tolerable dose was significantly lower and efficacy was better during combination therapy than with monotherapy, suggesting an additive interaction between the two drugs (38).
The eradication efficacy was better in the sequential group than in the triple group, both with ITT analysis (83.5%% vs. 77.3%%) and PP analysis (88.1 % vs. 85.0 %).
We found that for the shifting means model, –LOG(P) performed better than SD(T) did; however, for the outliers model, the identification efficacy was better for SD T).
In contrast, Schukken et al. [ 9] found a reduced duration of S. aureus IMI in vaccinated cows, and that vaccine efficacy was better in primiparous cows than in older cows.
To determine whether parents of Very Low Birth Weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU) transitioning home with the NICU-2-Home smartphone application have greater parenting self-efficacy, are better prepared for discharge and have shorter length of stay (LOS) than control parents.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com