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The discovery of a binding mode switch for the thiazolidinone in compound 7 and the highly ligand efficient lead 13 provides a potential starting point for lead optimisation chemistry, although cellular efficacy was a potential issue for this series (best in class T. brucei EC50: 6.3 μ m).
Self-efficacy is a potential resiliency factor that can mitigate the influence that pain-related fear has on outcomes in youth with chronic pain.
Legal tech holds tremendous potential, but its efficacy is a footnote to the culture it operates in and the business models from which it is deployed.
The identification of a group of structurally related compounds with potential therapeutic efficacy is an unexpected observation.
This lack of self-efficacy regarding sex and fertility is a potential barrier to seeking proper reproductive health care.
"But," he said, "there is a potential loss of efficacy.
Irradiation is a potential alternative to chemical fumigation for wood products; however, data supporting its efficacy against potential forestry pests is limited.
By establishing the PwMS as full partners to their care providers in health care decision and implement strategies to coordinate care between primary care and outpatient hospital care there is a potential to increase efficacy/outcome of care.
These activities could be important in relation to finding out its unexplored efficacy and can be a potential source of chemically interesting and biologically important anticancer drug candidates.
Neither the optimal dose of PDE 5 inhibitors nor the optimal parameters of efficacy are known for a potential use of these drugs in liver cirrhosis.
Daily hemodialysis (DHD) is associated with improvements in hypertension, left ventricular hypertrophy, mineral metabolism, nutrition, and quality of life, but efficacy is uncertain because of potential selection bias.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com