A number of these compounds are currently entering clinical trials and their efficacy will be evaluated in the next few years.
The health states are divided into "ACR20-response" or "no ACR20-response" leading to continuation of current treatment and "severe AE" or "lack of efficacy" leading to the next treatment in the sequence.
When an innovation has been developed, has amassed some or sufficient evidence of safety and efficacy in human studies, the next step is to determine whether the intervention is ready for scaling-up for delivery.
Ongoing clinical studies are expected to reveal the safety and efficacy of biomaterial-assisted regenerative medicine in the next few years, although much more effort is required for the ultimate clinical translation.
More recently, we have observed that three months treatment with bio-optimized curcumin significantly decreased sColl2-1 level in 24 patients with knee OA, suggesting that sColl2-1 could be a companion marker to assess curcumin efficacy at an individual level and in the next phases of its clinical development.
The crew on Stage 9 at Babelsberg Studio, near Berlin, erupted in a din of professional efficacy, preparing for the next shot, while Hanks returned to his chair to sip coffee from an NPR cup.
"Future studies demonstrating protective efficacy will be the next critical milestone for continued development of this promising vaccine approach".
This condition markedly decreases every next vaginal procedure's efficacy in the treatment of stress urinary incontinence and causes periurethral pain syndrome [ 11].
Because one assay may not accurately reflect the ability of a drug to increase seizure resistance, we next investigated compound B efficacy in the fluorothyl paradigm, an established seizure induction model involving exposure of the animal to the volatile proconvulsant bis-2,2,2-trifluoroethyl ether.
Such examples show the efficacy of data integration analysis and it is an easy prediction that in the next future more applications will be reported in the literature.
