Sentence examples for efficacy in causing from inspiring English sources

All forms have demonstrated efficacy in causing tumor regression in animal studies, which provides strong rationale for advancing IL-15 superagonist through clinical trials.

Cetuximab and trastuzumab have shown limited efficacy in causing remission in a proportion of patients with metastatic colorectal cancer and breast cancer respectively [ 21, 22], while trastuzumab has improved survival of women with ErbB2 positive breast cancer when given as adjuvant therapy after chemotherapy [ 32- 34].

Calcein has also been previously utilized to evaluate the efficacy of peptides in causing membrane perturbation [50].

In addition to hairy cell leukaemia and CML, therapeutic efficacy of IFN-α2 in causing at least partial disease regression has been identified in other diverse human malignancies including melanoma, renal cell and bladder cancer, lymphoma, myeloma, and Kaposi's sarcoma [ 6].

In contrast, there was no evidence of pathogenicity caused by A581 G-bearing parasites in Malawi, and SP retained some efficacy in preventing illness caused by malaria during pregnancy (J. Gutman et al., unpub. data).

20 Cost-minimisation analysis is appropriate only if the difference in cost is so large that no plausible difference in efficacy could cause the more costly treatment to be cost-effective.

A systematic review on the effectiveness of fosfomycin in the treatment of infections caused by MDR Enterobacteriaceae 10 was published in 2010; the existing information on the efficacy in systemic infections caused by these microorganisms was virtually non-existent; moreover, they were limited to a few small series of cases in which they were used in combination with other active drugs.

In our study, FECH siRNA significantly enhanced 5-ALA-PDT efficacy in glioma cells caused by marked growth inhibition and abundance of apoptotic cells under unchanged above parameters except for photosensitizer (PpIX) concentration.

Oral linezolid has excellent pharmacologic profile (bioavailability >99% and serum protein binding rate 30%) and there is a growing body of evidence of its efficacy in serious infections caused by Gram-positive cocci [ 39].

We show that age-related changes in autograft efficacy are caused by a loss in endogenous Wnt signaling.

IFN-γ administration in RA shows minimal efficacy and caused disease exacerbation in multiple sclerosis.