Sentence examples for efficacy has been established from inspiring English sources

Although its efficacy has been established, data are conflicting whether it is safer than neostigmine traditionally used for reversing NMB.

Once efficacy has been established, issues of generalisability will be addressed in future research.

Neither long-term safety nor cardiovascular outcome efficacy has been established for children.

Dabigatran, apixaban, and rivaroxaban safety and efficacy has been established for long-term secondary VTE prevention compared with placebo.

Internet interventions have a large potential for public health impact, and their efficacy has been established over the past 10 15 years.

While vaccine efficacy has been established for genotype 4, there are no studies in patients with genotype 1 or 2, the prominent strains in Africa.

The high rate of comparisons with vehicle controls in randomized controlled trials that assessed the efficacy of pimecrolimus or tacrolimus long after efficacy had been established is a matter of concern.

However the major disadvantage with conducting an efficacy trial in infancy (but not necessarily with deployment in this age group once efficacy had been established) is that disease end points can be difficult to define [20].

The therapeutic effects of rebamipide ophthalmic suspension are considered to be due to the increase of corneal and conjunctival mucin, and its safety and efficacy have been established in clinical trials and some experimental reports.

Therefore, randomized clinical trials with inherent internal validity, but with greater ecological and external validity – pragmatic, randomized trials – are required in real-world settings after safety and efficacy have been established.

New capacity in high disease burden countries to manage complex, large-scale efficacy trials has been established, and historical clinical trials offer crucial insights into the biology of TB.