There are, to date, no known MYC-targeting drugs, and given the importance of MYC upregulation in not only MM but also other tumors, JQ1 could be a future cancer therapy if its efficacy gets confirmed in in vivo models.
There's a great price point and the know-how that the Hubble executive team has in terms of safety, efficacy and getting word out to wearers of contact lenses.
At one time, the Senate Intelligence Committee investigated the CIA's contacts with Bigelow and Boal and whether the CIA was responsible for the film's depiction of torture and its efficacy in getting a courier to give up information that lead to bin Laden's location, but little came of the probe.
However, in contrast, we found that self-efficacy to get circumcised despite cultural barriers, and behavioral beliefs about healing and possible disfigurement, were significant in explaining MC motivation.
We are not getting 100% efficacy [with generic medications].
(R3, hospital) We are not getting 100% efficacy [with generic medications].
And her alacrity was matched by her efficacy: she always got the case moving, and she persisted until it was resolved.
Finally how to evaluate multiple drugs in an era of limited placebo controlled trials are discussed and the chapter ends with the competing demands of the shortest trials to get efficacy answers for immediate goals versus the value of long term studies for future outcomes and long term safety.
According to Hu, the situation in the village is getting worse because the efficacy of medication provided by the state is declining.
Many studies have shown the efficacy of computer-based interventions in getting college students to reduce their alcohol consumption.
On Tuesday, the F.D.A. held a public meeting to review facial fillers and to examine whether their popularization is getting ahead of safety and efficacy studies.
