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Additional advantages of combined RAF and MEK inhibition were the broader range of efficacy exhibited across melanoma cell lines and the ability to overcome vemurafenib drug resistance.
The GWH1-based nanoparticles combine clinically appealing properties of nanoscale materials with full biocompatibility, structural and functional plasticity and biological efficacy exhibited by proteins.
Falling was strongly associated with low falls efficacy, exhibited by a significantly lower MFES scores in fallers versus non-fallers.
The researchers believe the antioxidant properties of garlic, along with the chelating efficacy exhibited, led to the success of the treatment.
In our study, there was not a significant difference in the antimicrobial activity between drug in solution and nanoparticles probably due to the high efficacy exhibited by drugs at low concentrations.
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Efficacy and clearance of analogs decreased linearly with increasing log D values; efficacy exhibiting a steeper decline relative to clearance.
In contrast, at higher concentrations, the drugs lose efficacy, exhibiting the common U-shaped curve observed in the literature.
The model with constant ITN-efficacy exhibits a backward bifurcation emphasizing the need for sustained control measures until the basic reproduction number, R0, drops below a critical value at which control is feasible.
A higher efficacy was exhibited by ZnO-NPs compared to Ag-NPs.
Moreover, the PE PDMAE-BC membrane module can endure general water rinsing with little loss of antibacterial efficacy and exhibited an excellent antibacterial stability.
The efficacy was exhibited in the deanxit group, with evidence for similar safety.
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