Exact(8)
The drugs currently employed have limitations such as poor efficacy, drug resistance or side effects.
Currently, MCTS have also been widely exploited in drug delivery system research for comprehensive study of drug efficacy, drug penetration, receptor targeting, and cell recruitment abilities.
To test this hypothesis, we should establish animal models for studies including drug efficacy, drug safety, drug toxicology, drug metabolism and drug kinetics.
Formulation parameters such as PLGA molecular weight, concentration of ATV and PLGA in the coating solution and number of coatings were investigated to optimise the mesh in terms of drug loading efficacy, drug release kinetics and mechanical properties.
The drug response was controlled by the combined effects of drug efficacy, drug transport limitations, cell growth, and angiogenesis.
Studies that directly compare the new extended-release formulation with standard dosing should be conducted to further assess efficacy, drug adherence, and caregiver burden.
Similar(52)
Poor vaginal efficacy, drug-resistance and non-spermicidal nature limit their use as topical microbicidal contraceptives.
Because atomoxetine has demonstrable efficacy, drug-placebo response curve analysis of its performance against placebo was warranted.
This multi-scale simulation study provides microscopic insight into the mechanisms of drug loading and releasing, and might be useful for the design of new materials for high-efficacy drug delivery.
Drug efficacy reflected drug type and regimen, acceptance of testing and adherence to treatment.
To optimize treatment, we used a mathematical model describing the pharmacokinetics of anticancer drugs, antitumor efficacy, and drug toxicity.
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