Sentence examples for efficacy decrease from inspiring English sources

Glyco-engineering of host cells is used to increase efficacy, decrease immunogenicity and increase circulatory half-lives of protein biopharmaceuticals.

A high probability of risk-related treatment efficacy (decrease in log-odds mortality with increased control arm risk) was identified by metaregression in the low dose trials (n = 9, slope coefficient -0.49 -1.14, 0.27); P = 92.2%).

Knocking out P-gp from the ALS mice improved significantly the therapeutic effect of riluzole (Fig. 2E), further strengthening the assumption that as ALS progresses in mice and Pg-p and BCRP increase, 12 riluzole penetration and efficacy decrease.

Efficacy decreased with advancing gestational age.

The transfer efficacy decreased with increasing air exchange rate and supply air temperature.

For example, solubilized colistimethate sodium (CMS) is not stable and its antimicrobial efficacy decreases over time [15].

While in the third stage, the embankment is unable to form a new stable soil arching and the efficacy decreases gradually.

The NPs' size-dependent efficacy decreases away from the NPs' size of minimum absorption bandwidth, which is around 20 nm for Au NPs or other shapes of equivalent surface area volume ratio.

In sepsis, average efficacy decreased from 15 to 60 min (P = 0.006, Wilcoxon matched-pair signed ranks test), whereas it did not differ between the different time points in hemorrhage (P = 0.108).

This efficacy decreased when the amount of clays was reduced, with higher values (P<0.001) for Atox® compared with Novasil™ Plus (0.50 vs. 0.28 in CTR; 0.58 vs. 0.16 in LRS and 0.44 vs. 0.27 in HRS).

This reduces seizure probability; 4) The anti-inflammatory efficacy decreases over time.