But Jeremy Anwyl, the chief executive of Edmunds.com, is dubious of the office's efficacy to date.
The standard clinical technique for using repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder (MDD) is associated with limited efficacy to date.
However, the limited efficacy to date combined with the scarce availability of human fetal tissues and ethical concerns render this procedure inapplicable to a wide population scale.
Although ACT utilizing ex vivo expanded tumor-infiltrating lymphocytes (TIL) or engineered CAR/TCR T cells have undergone clinical trials for other solid cancers, their efficacy to date has been limited.
On-demand, localized control over delivery of rhBMP-2, days after implantation, would therefore be an attractive solution in the area of bone repair and reconstruction, yet this has posed a significant challenge, with little data to support in vivo efficacy to date.
Cytotoxic chemotherapy and hormonal agents have been tested in HCC with marginal efficacy to date.
Cytotoxic chemotherapy, hormonal agents, and immunotherapy have been tested in HCC with marginal efficacy to date.
The strongest evidence of efficacy to date supports DHTs that are included as part of in-person treatment as an adjunct or enhancement to current care.
Although immune checkpoint inhibitors have shown promising safety and efficacy, to date only a small proportion of patients have achieved long-term survival, with severe irAEs occurring on occasion.
Although lapatinib is considered an equipotent inhibitor of HER2 and EGFR, based on data from in vitro kinase assays [ 14, 15], its clinical efficacy to date has been limited to HER2+ breast cancers [ 16].
Conclusions about the overall efficacy of dating violence interventions are premature, but such programs are promising.
