Sentence examples for efficacy consideration from inspiring English sources

Any efficacy consideration in terms of clinically relevant treatment effects, however, implies some knowledge about the incidence of an event with placebo treatment.

The ability of DMTs to reduce markers of disease activity early in the disease course is an important long-term efficacy consideration because the presence of these markers, such as MRI lesion burden and clinical parameters, correlate with severe disability in the long term [ 170– 170].

Safety and efficacy considerations are important in optimizing the choice of an antiarrhythmic drug for the treatment of AF.

The dose regimen of anti-OX40L MAb in this study was chosen based on safety and efficacy considerations.

In Europe safety and efficacy considerations fall within the European Medicines Agency Guidelines on Risk Management Systems for Medicinal Products for Human Use[ 22].

These economic, acceptability and efficacy considerations make it imperative that there is further examination into the utility of online therapy for OCD.

This recommendation will be based primarily on safety and efficacy considerations and will be guided by statistical monitoring guidelines defined by the trial safety charter.

Future efficacy considerations will involve monitoring the emergence of regional strain variants, since the selective pressure of 4CMenB could potentially drive the emergence of escape mutants and may reduce vaccine efficacy.

No formal interim analyses are intended although the trial's Data Monitoring Committee (DMC) will meet regularly, have access to unblinded data and would recommend early termination to the Trial Steering Committee ifjudged appropriate based on ethical, safety or efficacy considerations.

They concluded that there was no clear agent of choice for prophylaxis based on efficacy considerations (ie ability to prevent clinically important bleeding), but sucralfate might have advantages in terms of adverse effects because it was associated with a lower incidence of pneumonia compared with histamine-blocking medications.

In addition to efficacy, other consideration for licensing of veterinary vaccines includes cost effectiveness, ease of administration, ease of metabolism, and minimal effects of carcass in food animals.