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ACR20 has been accepted as the efficacy benchmark in RA clinical trials, showing greater discriminant capacity over ACR50 and ACR70 to distinguish active treatment from placebo control.
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Taking this experience to beauty, one of my early goals was to prove that Juice Beauty's skincare products, made with certified organic ingredients, could certainly surpass the natural brands efficacy but I wanted to meet or exceed conventional chemical efficacy benchmarks.
Before translation to the humans, however, FUS-MB must pass vigorous safety and efficacy benchmarks to prove therapeutic benefit and minimize side-effects.
Their efficacy rivals benchmark detergents heavily used today, such as n-dodecyl-β-d-maltoside.
These specifications can be used to benchmark the efficacy of other environmental specifications also.
Consequently, durable polymer stents have been considered the benchmark for efficacy (restenosis), whereas bare metal stents have been considered the benchmark for safety (stent thrombosis).
Oxcarbazepine (OXC) is a 10-keto analogue of carbamazepine (CBZ) – the antiepileptic drug (AED) that has served as the benchmark for efficacy in partial-onset seizures.
Although there is currently no correlate of protection established for HPV-16/18 HPV-16/18, other recent large effinfectionals can prother benchmarecentr comparison.
At which point, the question becomes unavoidable: is efficacy now to be the benchmark for persecutors?
Because mupirocin has widespread use in S. aureus nasal decolonization, mupirocin provides a benchmark for the efficacy of antimicrobials.
Rifampin thus serves as an important benchmark: it has efficacy against persistent M. tuberculosis, so any strategy that does not have a rationale for a shorter therapy should not make the list of new targets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com