Sentence examples for efficacy as possible from inspiring English sources

Some experts say any treatments should not be given on a compassionate use basis, but should be part of a carefully conducted clinical trial, so as to learn as much about a compound's efficacy as possible.

Therefore, we have explored the impact of T. gondii-induced microlesions on the whole mouse brain neuronal circuitry as well as on the morphology of individual noninfected neurons, and we correlated the neuroanatomical alterations in those areas with changes in the synapse efficacy as possible contributing factors for the behavioral and neurological deficits.

Both inadequate efficacy as well as implementation is a possible reason for the lack of effect in some of the strength parameters.

Further in vivo investigations using animal models would be of value to corroborate our findings for the role of FasL/Fas and to test its efficacy as a possible therapeutic target.

In parallel, more 5,10-MTHF might be left for nucleic acid synthesis, decreasing MTX efficacy as one possible explanation of an association with overall survival observed in this cohort.

We could not identify self-efficacy as a possible predictor of HRQoL.

On the proposed mechanisms, however, the evidence is less conclusive with motivation and self-efficacy as identified as possible mechanisms for mental simulation effects.

In general, qualitative description of generalisability or quantitative extrapolation (modeling) should be used to transform efficacy data, as far as possible, to effectiveness data, i.e. to adjust data from controlled trials to what would be expected in clinical practice.

A U.S. government official who is involved with these discussions and asked not to be named says the government is helping to set up the efficacy studies as quickly as possible, and says their results should be awaited "before large sums of money need to be invested in scale up of production".

As there are very few new antibiotics in the late stages of the drug-development pipeline, it is critical to make best use of existing antibiotics to preserve their efficacy for as long as possible [ 2, 9].

We considered attitude, social norm and self-efficacy, knowledge/skills and stimuli, based on the Attitude - Social norm - self-Efficacy model (ASE model) as possible determinants of both intention and behaviour.