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The analysis showed that (1) knowledge has a central significance at this stage, but the authors have yet to agree on the best methods to impart and apply that knowledge; (2) no general framework has emerged as a validated approach to manage knowledge for requirements engineering; and (3) the evaluation marks for model efficiency and efficacy are low, consisting mostly of personal interpretations.
While you know fundamentally what it is that you seek to achieve (to see your friend again after so many years), your confidence and efficacy are low as you remain hazy about how you will finally achieve your objective.
Some experts suggest that CAM use is predictably increased in situations such as cancer, where "illness consequences are high and beliefs in the effectiveness of conventional treatments (i.e. response efficacy) are low" [ 7].
If perceived severity and susceptibility are high but response and/or self efficacy are low, maladaptive responses (e.g. denying the existence of a threat) are likely to ensue[ 10, 11].
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In situations where the RTS,S efficacy is low, the limited available resources may be better used for other efficacious interventions such as artemisinin-based combination therapies (ACTs), insecticide-treated mosquito net (ITN) and indoor residual spraying (IRS).
Sub-unit proteins offer a much safer alternative; however, their efficacy is low.
When political efficacy is low, people do not trust the government and they believe that their actions can hardly affect political leaders' action.
Or, fear appeals are only effective when the at-risk population has high (self-) efficacy, and they may actually be counter-effective when efficacy is low (Peters et al., 2013; Ruiter et al., 2014).
Dissemination of vaccines via mass campaigns, supplementing EPI, also has little impact on overall effect when the efficacy is low, but at low transmission, high efficacy and high vaccine coverage, when elimination is achieved, all but the earliest episodes are averted.
However, response and self efficacy were low.
Where efficacy is low, the requirement is for large numbers of patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com