24 Our study demonstrated that adding probiotics to standard triple treatment had the positive consequence of enhancing efficacy, and previous systematic reviews reached the same conclusion.
However, studies reported varying efficacies, and relevant systematic reviews have included clinical trials with inherent heterogeneity either in study conditions or types of interventions used.
However, their clinical efficacy and safety lack systematic evaluation.
Among all CHM used for PMS, only JWXYS was examined for its efficacy and included in systematic review [ 15, 17].
The study will examine the feasibility and efficacy of routine, systematic and regular use of the Guidelines and NAT: PD-C in a range of clinical settings in terms of their ability to facilitate the timely provision of needs based care for people with advanced cancer.
Despite their efficacy, the systematic and extensive use of anthelmintics causes concerns with regards to (i) the negative effect on the development of natural immunity, (ii) consumer concerns regarding drug residues in food products and the environment, and (iii) the increasing incidence of parasite resistance against available anthelmintics.
Taken together, there remains a substantial knowledge gap with respect to the efficacy and cost-effectiveness of systematic medication reviews, especially in the nursing home setting.
Furthermore, if such economic information is to conform to the standards of evidence used for clinical efficacy and remain free of systematic bias, it is essential that data are collected prospectively, in conjunction with RCTs, whenever possible.
To the best of our knowledge, our study is the first economic evaluation of atosiban versus betamimetics based on evidence of efficacy and safety from a systematic literature review, and assessing the differential costs of tocolysis from the payer's and provider's perspectives.
Based on meta-analyses and systematic reviews, the efficacy of fiber treatment in IBS is mixed; conclusions vary based on the different types of fiber used and, in part, on the different review methods employed [66 71].
