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However, unlike most proteins and peptides, NA must be delivered to the cytoplasm or nucleus to be efficacious, resulting in significant delivery challenges.
But the product was not clinically efficacious, resulting in the termination of the project.
We found that a lifestyle intervention program in obese endometrial cancer survivors is feasible and efficacious – resulting in sustained behavior change and weight loss over a one year period.
In addition, in the intracranial model, the combination treatment was more efficacious, resulting in a 73% decrease in tumour volume 25 days after the start of therapy, as well as in a longer survival of the animals.
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The combination of capecitabine and MMC is efficacious, results in symptom relief and is well tolerated as third-line treatment of metastatic CRC.
Previous studies have examined the effects of vIL-10 in the AIA rabbit model as well as the collagen induced arthritis mouse model showing efficacious results for treatment [ 11, 12, 32, 33].
This is potentially valuable, as drugs that have a robust efficacy in a client-owned canine model may be more likely to yield an efficacious result in human clinical trials.
We aimed to investigate the hypothesis that an initial administration of a short course of oral prednisolone would lead to more efficacious results from subsequent nasal steroid therapy in the treatment of nasal polyposis.
In light of the Phase III population level vaccine trial completed in Thailand in 2009, which only showed moderately efficacious results, it is important to understand how the media are communicating the reality of partial protection, and how individuals may understand partial protection risk messaging when, or if, it is communicated [ 24].
The prevailing view that endosymbionts have less efficacious selection, resulting from reduced effective population sizes (Moran 1996; Andersson and Kurland 1998; Woolfit and Bromham 2003; Fares et al. 2004), fits well with some features of Hodgkinia genome, in particular with its tiny size and overall rapid rate of sequence evolution.
Furthermore, the CT-tagged ADC appeared to be the most efficacious conjugate resulting in the highest log10 cell kill.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com