This is particularly relevant for the definition of novel, more efficacious hormonal replacement therapies or for the evaluation of the risk associated with the exposure to endocrine disruptors.
To date, a truly efficacious DDT replacement has not been found and one may never be found because of the true nature in which DDT functions.
Although enzyme replacement therapy is efficacious, it is also very inefficient, with less than 1% of the infused enzyme making it to the target tissues in some treatments.
Herein we will review the role of the mitochondria in the myocardium following myocardial ischemia and provide evidence to show that the augmentation or replacement of mitochondria is efficacious.
Subsidizing nicotine replacement therapy (NRT) is efficacious in significantly increasing cessation rates and the number of cessation attempts by smokers wanting to stop smoking [ 40].
The presence of inhibitors generally precludes the efficacious use of FVIII and FIX replacement therapy, especially in patients with high-responding and high-titre inhibitors, due to an anamnestic response.
A six week functional exercise programme from week 12 to week 18 in patients post total hip replacement will be more efficacious in improving pain, stiffness and function than the usual care programme.
A six week functional exercise programme from week 12 to week 18 in patients post total hip replacement will be more efficacious in improving balance, gait speed, quality of life and muscle size than the usual care programme.
This study was motivated by recent findings of variability in health outcomes following TKA. 3 It should be emphasised that the intention of this study is not to assess whether knee replacement surgery is an efficacious intervention; it would be inappropriate to draw inferences about this from our study.
Efficacious pharmacological therapy include alendronate, risedronate, hormone replacement therapy, strontium ranelate, that are successful agents for femoral and vertebral sites.
In critically ill, patients with AKI at high risk of bleeding, CVVH with citrate-containing replacement solution is safe and efficacious.
