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Patients then underwent a therapy titration period during which stimulation parameters were adjusted bi-weekly as necessary; upon identification of efficacious parameters, or if efficacious parameters could not be identified and the neurostimulator lead positioning was considered correct, patients were moved into the experimental period.
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Interestingly, 'IL water content' is found to be the most efficacious parameter in the extraction process while 'time' retained a nominal impact.
However, questions remain regarding the efficacious stimulation parameters.
In these studies, liraglutide was more efficacious in lowering glycemic parameters compared with the comparators and additionally led to a significant weight loss (11).
In responders following treatment, the R2* value has been shown to increase, likely as a result of decreased blood flow; however, in this one published study this parameter was not as efficacious as changes in other DCE-MRI parameters, such as Ktrans, rBV, and rBF, or even morphological parameters such as tumour size, in indicating response [ 36].
The methodology has been shown efficacious in determining the solubility parameters of oils even in those oils with low content of asphaltenes and a high amount of particles in suspension, where other methods had not yielded a good performance.
As such, screening tools, which neglect to include relevant parameters, may be less efficacious in identifying malnutrition risk.
Major challenges exist in terms of appropriate patient selection and optimisation of the stimulation parameters to obtain an efficacious response.
Also, because of uncertain parameters of the model, an efficacious possibilistic robust optimization approach was applied.
Also, because of the uncertain parameters of the model, an efficacious possibilistic robust optimization approach is utilized.
Likewise, studies on steroidal estrogens used in hormone replacement have shown that some B-ring unsaturated compounds have distinct tissue-selective actions, being more efficacious in vasomotor, neuroendocrine and bone preservation parameters than in other peripheral actions of estrogens [ 28*].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com