It is important to note that psychiatrists have decreased their LAI prescribing rates in the last five years by approximately 50%, although LAIs are shown to be very efficacious, are associated with higher compliance rates, and are currently more available [ 25].
With these findings, albumin nanosphere-loading approach might be efficacious to improve the antitumor activity of gemcitabine, and the efficacy is associated with the size of GEM-ANPs.
Although efficacious, insulin is associated with side effects such weight gain and hypoglycemia (1, 14).
Trastuzumab in combination with doxorubicin or epirubicin is highly efficacious but is associated with an extremely high frequency of cardiotoxicity [ 12].
Sublingual spray is the preferred method of administration since it is the most efficacious and is associated with fewer side effects [ 9, 10].
Nonetheless, the balance of evidence suggests that reduced asexual parasite density (as would be achieved by an efficacious BSV) is associated with reduced infectivity to mosquitoes.
It is efficacious but is associated with a high incidence of dose-limiting side effects, namely dizziness (28% versus 8% for placebo) and somnolence (21% versus 5% for placebo).
Improving glycaemic control through timely and intensive diabetes treatment reduces the risk of developing complications in patients with diabetes 1, 2. With appropriate titration, insulin therapy is highly efficacious but is associated with hypoglycaemia.
Therefore, the addition of capecitabine to MMC may be less efficacious than these combinations, but is associated with a more acceptable toxicity profile.
In summary, this study confirms that therapy with exenatide is efficacious in improving metabolic control, which is associated with a significant weight loss in patients with type 2 diabetes, irrespective of sex.
