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These viruses have also been well characterized, extensively studied for primate responses, and have been found to be efficacious in generating antibodies.
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Alternative platforms to construct ZFNs have since emerged, and these show variation in speed, site selection and success in generating efficacious ZFNs (Sander et al., 2011; Gupta et al., 2012; Bhakta et al., 2013).
Indeed, the human immune system itself can safely be assumed to be the best in generating highly efficacious antibodies and these antibodies are most likely superior to those generated from mice or using phage display.
Based on this structural information, we predict that it will be possible to generate LCBs that are highly efficacious in killing bacteria without causing effects on the host.
Pacritinib was highly efficacious in blocking tumor growth in mouse subcutaneous xenograft models generated with the FLT3-ITD-harboring cell lines, MV4-11 and MOLM-13.
First, our study may suggest that though much less efficacious in inducing presynaptic dopamine levels in the ventral striatum, sweet consumption may nevertheless generate an overall postsynaptic dopamine signal more intense than cocaine.
Differences in efficacy were syndromal, i.e. more or less efficacious in neuralgias than in persistent facial pain. .
Data generated in the present small pilot trial suggest that a proprietary bioactive extract of chicory root might be efficacious in patients with OA of the hip or knee.
I figured a "blockbuster" drug would be efficacious in more than 50percentt of the people who took it.
Lamotrigine was very efficacious in the treatment of our patient.
Repeated EBPs are efficacious in many refractory SIH [86].
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