Whereas TAM was equipotent to EE in eliciting uterotrophy in C57BL/6 mice and Sprague-Dawley rats, it was 43% less efficacious in both species eliciting only 4- and 5-fold induction (in the rat and mouse, respectively) compared to the ~9-fold increase induced by EE.
If postcard prenotification is found to be equally efficacious in terms of eliciting response, then cost savings can accrue to investigators as postcards are much less expensive to mail.
We have demonstrated previously that this is the most efficacious dose for eliciting skeletal muscle hypertrophy in rodents [ 3].
In general, efficacious TAM elicited responses were associated with receptor-mediated signal transduction, ion transport and protein metabolism.
Of relevance, co-administration of granulocyte-macrophage CSF factor and recombinant interferon gamma 1b in concert with carboplatin treatment in women with recurrent ovarian cancer was shown to be efficacious and elicited a favourable haematological profile (Schmeler et al, 2009), providing a potential option in this regard.
But no similar claim can be made about the person whom God moves, by efficacious grace, to elicit a meritorious volition.
Our data thus suggest that HIVBr18, like some validated efficacious vaccines, can elicit polyfunctional T cells, a putative correlate of protection.
It appears that this MPD dosage attenuated the average acoustic evoked responses by 19.8%, 27%, and 29.5% in the VTA, NAc, and PFC, respectively, while the same MPD dose (0.6 mg/kg) was not efficacious enough to elicit a behavioral (locomotor) response.
Meningococcal polysaccharide vaccines are efficacious in preventing IMD in adults but do not elicit long-lasting immunological memory.
