Sentence examples for efficacious in developing from inspiring English sources

However, these oral vaccines are less efficacious in developing countries [ 4, 5] and are associated with safety concerns such as a risk of intussusception [ 6].

It seems reasonable that targeted inhibitors, optimized by using structure-based drug-design with monitoring of PK parameters and inhibition of human CYPs involved in metabolism of xenobiotics, will be more effective in developing efficacious treatments of human T. cruzi infections compared to use of repurposed antifungal agents.

It is likely that parasite-specific inhibitors, optimized by structure-based drug-design criteria with close monitoring of PK parameters and inhibition of human drug-metabolizing CYPs, will be more effective in developing efficacious treatments of human T. cruzi and other protozoan infections than the antifungal agents.

Currently available live RV vaccines are efficacious but show lower efficacy in developing countries, as well as a low risk of intussusception.

In multicenter trials, monovalent and pentavalent rotavirus vaccines were safe and highly efficacious for children in developing countries (2 ).

Thus network biology has played a central role in developing efficacious therapies that alter entire pathways rather than single proteins, resulting in the potential for fighting complex multifactorial diseases [3].

Understanding these underlying mechanisms of postural control with load carriage strategies in humans could productively help in developing efficacious preventive strategies to reduce the incidence of falls from inclined slopes.

One of the major hurdles in developing efficacious direct drug conjugates is releasing active drug from the targeting agent.

Identification of such molecular mechanisms will help greatly in developing efficacious medications for the treatment of METH dependence.

Despite the high rate of HIV diagnosis among African American MSM, limited progress has been made in developing efficacious interventions for this population.

However, there has been considerable difficulty in developing an efficacious malaria vaccine, highlighting our incomplete understanding of immunity against this disease.