Given how little research has been devoted to pediatric TTM and its treatment, this study represents an essential step in identifying and implementing efficacious treatments for youth with TTM.
The cornerstone in implementing efficacious ARV regimens is identification of HIV-positive pregnant women in need of cART for their own health.
Implementing efficacious health service intervention in a real-world resource-constrained setting is challenging and may not prove effective in improving patient outcomes.
However, it also highlighted three key bottlenecks in implementing efficacious ARV regimens: (1) capacity to assess CD4 count, (2) availability of CD4 count results at clinics, and (3) capacity to initiate cART.
One concern with regards to implementing partially efficacious vaccines is the issue of behavioral disinhibition, which occurs when vaccinated individuals believe they are protected from HIV infection and therefore increase the behaviors that put them at greater risk of exposure to HIV [6].
Implementing an efficacious health service intervention in a real-world resource-constrained setting is challenging and may not prove effective in improving patient outcomes.
21 This science-driven misapplication of the Public Health Model ignores the importance of engaging practitioners, policy makers and the community in the process of designing, researching and implementing effective interventions, falsely assuming that efficacious interventions can be automatically adopted and effectively implemented at a population level.
Valid tests are an essential tool to evaluate a nation's educational standing and to implement efficacious educational reforms.
To reduce the burden of chronic illness, prevention and management interventions must be efficacious, adopted and implemented with fidelity, and reach those at greatest risk.
Adapting and testing interventions proven to be efficacious in similar cultures might circumvent the time and costs of implementing evidence-based interventions in new settings.
