New drugs that are safe, efficacious, and impact a larger proportion of individuals with PKU are needed.
We predict that reduced lethality through poor SIT methods or imperfectly efficacious vaccines will impact efforts to control disease spread.
Nursing care factors impact on efficacious performance of DIS.
To assess the efficacy of a novel ultraviolet (UV) lens device on the killing of Acanthamoeba cysts and the impact of efficacious doses of UV upon soft contact lens parameter and material characteristics.
Given that the currently available treatments to prevent HIV transmission and disease are not effective in eradicating the virus, vaccination likely represents the only efficacious adapted response to the global impact of this infection.
Even in a country with a concentrated epidemic, disinhibition will be a great challenge with the potential to negate the impact of a partially efficacious HIV vaccine.
To have an impact on public health, efficacious PHC-based PA interventions need to be effectively introduced in practice.
Next, we investigated the molecular mechanisms underlying the anti-inflammatory impact of the most efficacious fraction of HCE, the HCE ethyl acetate fraction (HCE-EA).
Furthermore, at the Global Pertussis Initiative meeting in Paris 2010, members stressed the need of efficacious surveillance systems to evaluate the impact of dTap booster on the disease incidence in adolescents [ 66, 69].
To control the disease in either endemic situations or in case of large, high-impact contingencies, safe and highly efficacious live attenuated vaccines exist since decades.
