Sentence examples for efficacious immune response from inspiring English sources

This observation suggests that a shift in cytokine production levels could be important in providing a more efficacious immune response to brucellosis.

The results suggest that the epitopes found here are good candidates for establishing a peptide vaccine that can trigger an efficacious immune response in vivo.

During the last decade, the propagation of immunological knowledge describing the critical role of dendritic cells (DC) in the induction of efficacious immune responses has promoted research and development of vaccines systematically targeting DC.

The current results show that the cell-based H5N1 viral antigens produced from SF medium could induce strong and efficacious immune responses similar to those obtained from the H5N1 virus produced from the SC medium reported in our previous study [4].

However, subcutaneous vaccination with genetically modified cytokine-secreting tumour cells has been demonstrated to be efficacious against intracranial tumours in a murine model, which supports the notion that an effective immune response can be generated against intracerebral tumours (Dranoff et al, 1993; Sampson et al, 1996).

First, we considered an effective immune response.

Although this vaccine is highly efficacious the immune response is short-lived and re-immunization is required.

In the case of immunogenic tumours, single-agent CTLA4 blockade was enough to induce tumour shrinkage, whereas in other models anti-CTLA4 synergised with other treatment modalities to induce efficacious antitumour immune responses (reviewed in [35]).

Since nanosized materials often exhibit unique properties that may offer significant advantage for biomedical applications (Jain 2008; Martin and Kohli 2003), it is sensible to investigate if nano-alum will be more efficacious in enhancing anticancer immune response than conventional alum.

Although the mechanistic underpinnings of immune priming are not well understood (but see [ 6, 7]), what is clear is that the innate immune response is more efficacious after a preliminary encounter [ 8].

These potential tumor antigens, however, do not usually generate a strong immune response, or the response is not efficacious.